Fatty15 Review – How Does It Compare to Omega-3 & Other Fatty Acid Supplements?

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As a very health-conscious person, supplements have always been a key part of my daily routine. One of those has been fish oil pills – I’d read that they help with inflammation and vitamin D absorption, so I’ve been incorporating them since.

Recently, though, I came across new research on another essential fatty acid, C15:0 – the “first essential fatty acid to be discovered since the omegas” and thought, do I really need an omega-3 alternative? What’s all the buzz about fatty15? How can this benefit me?

I want to help answer all that and more for you – what C15:0 is, how it compares to other fatty acid supplements, the benefits it can provide, and if it’s worth it to include fatty15 in your daily supplements.


TLDR: Cutting to the chase

C15:0 (also called pentadecanoic acid) is clinically proven to boost cellular health significantly more than even the purest omega-3 supplements. But it’s not just another omega-3 supplement – it’s better, broader, and safer at repairing cells and restoring cellular health.


It’s now the third recognized essential fatty acid and is the single ingredient in fatty15’s daily supplement created to promote healthier cells, improve metabolic, heart, and liver health, and protect against aging-related breakdown.




  • Near-term benefits: Better sleep, calmer mood, less anxiety, more energy, less hungry – can be felt within the first few weeks of taking.
  • Long-term benefits: Improves cellular resilience, promotes healthy skin, glucose levels, and cholesterol levels, and supports liver, metabolic, heart, immune, and red blood cell function.
  • Vegan: Unlike many omega-3s, fatty15 is vegan, tasteless, and odorless (no fish burps!!). Also, lactose and gluten-free with no preservatives.
  • Higher quality: You know exactly what you’re getting, where many omega-3 supplements vary in quality, levels of fish oil, contaminants, shelf-life, and smell, plus they negatively impact ocean life.
  • Longer shelf life: Doesn’t include oils that oxidize over time, so they won’t rancid in the bottle or in your body (like many omega-3 supplements)
  • Scientifically Validated: Breakthrough discovery backed by a robust collection of more than 50 reliable, peer-reviewed scientific studies.
  • Limited Availability: You can’t buy fatty15 at local grocery stores or pharmacies on demand. It is currently only available through fatty15’s website directly.
  • Synthesized Product: The single ingredient in fatty15 (FA15™) isn’t sourced from fish. It was, however, carefully synthesized to mimic the exact properties of pentadecanoic acid (C15:0) while being >99.5% pure, environmentally sustainable, vegan-friendly, more bioavailable, and meeting diverse dietary needs.

Fatty15 review: Why is it suddenly getting all the hype?

For more than 90 years, alpha-linolenic acid (omega-3) and linoleic acid (omega-6) were the only known fatty acids to meet the criteria for being considered “essential”. Essential fatty acids support our cells and balance our immune system, but our body doesn’t make them naturally.


To understand why this new pentadecanoic acid (C15:0) supplement is such a big deal, the discovery story is worth telling. Fatty15 began with observations of dolphins and led to ground-breaking research for the benefit of everyday people.




Yeah, but think about it – they’re a lot like us. They live for a long time, they’re social and intelligent, and they, too, can develop aging-related conditions.

Stephanie (DVM, MPH) and Eric (MD, MBA) Venn-Watson were studying why some dolphins developed chronic inflammation, arthritis, high cholesterol, and other diseases later in life while others did not.

This led to the discovery that healthier dolphins comparatively had a different composition of dietary fatty acids. It was originally assumed that the healthier dolphins would have more omega-3 fatty acids based on their locations and the fish available to eat, but it turned out the healthier dolphins actually had higher compositions of an entirely different fatty acid (you guessed it): C15:0.

But what does that have to do with YOU?

Those same fatty acids that dolphins need to stay healthy are also needed by your body for healthy aging. With this C15:0 breakthrough, the single pure ingredient in the fatty15 supplement was created: FA15™.

FA15™ is a >99.5% pure, patented C15:0 powder that harnesses the properties of C15:0 found naturally in some fish. Stephanie and her team worked closely with the Navy to develop this unique ingredient, and there’s significant scientific support for its effectiveness, along with a slew of awards and scientific publications that are now recognizing this pentadecanoic acid supplement for all of its amazing benefits.

It’s the omega-3 alternative we didn’t know we needed.


Fatty15 benefits: What is C15:0 good for?

Fatty15 contains the odd-chain saturated fatty acid known as C15:0. One study published in The Journal of Nutrition found that humans with higher levels of dietary odd-chain saturated fatty acids, including C15:0, had better long-term health, supporting the need to maintain levels in our body to stay healthy.

Simply put: Fatty15 is a daily oral supplement that works to offset age-related cellular breakdown. The single ingredient – a >99.5% pure C15:0 powder – is a newly discovered essential fatty acid that’s gone through extensive scientific studies. It’s been shown to support bodily functions like regulating metabolism, immunity, mood, sleep, and appetite.


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Because everyone is different, some will feel a difference after taking fatty15, while others may not. About 2 out of 3 people report feeling fatty15’s near-term benefits, which can be experienced within the first few weeks, including:


  • Deeper, better quality sleep
  • Calmer mood, less anxiety
  • More energy throughout the day
  • Less snacking and less hunger between meals

The longer-term benefits have been backed by substantial scientific evidence and can take 1 to 3 months to start working.


Improves cellular signaling

Cells throughout your body are constantly sending and receiving signals from their surrounding environments, which are critical to metabolic regulation, like cholesterol and glucose homeostasis. C15:0 helps improve the signaling process by binding to cellular receptors known as PPARs (“pee-pars”). One study even found that C15:0 can inhibit signaling in breast cancer cells.


Supports the nervous system

By binding to PPAR receptors that control mood and sleep, C15:0 helps support a balanced mood and helps you rest better in as little as 45 days of continued supplementation.


Boosts Long-term heart health

People who used C15:0 for fatty acid supplementation demonstrated improved tissue and organ function health markers in as little as six months. One scientific study found that odd-chain essential fatty acids, including C15:0, had a significant inverse association with coronary heart disease. Higher levels of those essential fatty acids meant a lower risk of heart disease


Helps with mood regulation

One metabolite of C15:0 is an endocannabinoid, which are chemicals naturally created in the brain that have the same impact as cannabinoids like CBD. It attaches to CB1 and Cb2 receptors that control mood regulation, anxiety, and other emotions. Taking fatty15 consistently can lead to significant antidepressant effects and more pleasant moods.


C15:0 vs Omega-3: Which fatty acid supplement is better for you?

With all this info, that’s the new big debate. Is one better for your health, should you be taking them together, should one replace the other?


While both support immune and metabolic health, there are some key differences.

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